{"id":177,"date":"2022-06-08T12:25:00","date_gmt":"2022-06-08T04:25:00","guid":{"rendered":"https:\/\/www.helixmatrix.net\/?p=177"},"modified":"2025-04-12T21:48:52","modified_gmt":"2025-04-12T13:48:52","slug":"%e5%9f%ba%e4%ba%8ecfdna%e7%89%87%e6%ae%b5%e5%8c%96%e6%a8%a1%e5%bc%8f%e7%9a%84%e6%b3%9b%e7%99%8c%e7%ad%9b%e6%9f%a5%e6%a8%a1%e5%9e%8b%e7%9a%84%e4%b8%b4%e5%ba%8a%e7%a0%94%e7%a9%b6","status":"publish","type":"post","link":"https:\/\/www.helixmatrix.net\/index.php\/2022\/06\/08\/%e5%9f%ba%e4%ba%8ecfdna%e7%89%87%e6%ae%b5%e5%8c%96%e6%a8%a1%e5%bc%8f%e7%9a%84%e6%b3%9b%e7%99%8c%e7%ad%9b%e6%9f%a5%e6%a8%a1%e5%9e%8b%e7%9a%84%e4%b8%b4%e5%ba%8a%e7%a0%94%e7%a9%b6\/","title":{"rendered":"\u57fa\u4e8ecfDNA\u7247\u6bb5\u5316\u6a21\u5f0f\u7684\u6cdb\u764c\u7b5b\u67e5\u6a21\u578b\u7684\u4e34\u5e8a\u7814\u7a76"},"content":{"rendered":"\n<p>cfDNA\uff08cell free 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\/><\/figure>\n\n\n\n<p>\u8bb8\u591a\u7814\u7a76\u8005\u7814\u7a76\u4e86\u4e0d\u540c\u764c\u75c7\u65f6\uff0ccfDNA\u5bf9\u80bf\u7624\u590d\u53d1\u53ca\u75c5\u4eba\u751f\u5b58\u671f\u7684\u9884\u540e\u4ef7\u503c\u53ca\u5bf9\u6cbb\u7597\u53cd\u5e94\u7684\u76d1\u6d4b\u3002\u5728\u60a3\u4e73\u817a\u764c\u3001\u7ed3\u76f4\u80a0\u764c\u3001\u809d\u764c\u3001\u80ba\u764c\u3001\u80c3\u764c\u3001\u5375\u5de2\u764c\u548c\u524d\u5217\u817a\u764c\u7684\u75c5\u4eba\u4e2d\uff0c\u5927\u591a\u6570\u75c5\u4f8b\u51fa\u73b0\u8f83\u9ad8\u6d53\u5ea6\u7684cfDNA\uff0c\u662f\u75be\u75c5\u751f\u5b58\u671f\u4e00\u4e2a\u72ec\u7acb\u7684\u5371\u9669\u56e0\u7d20\uff0c\u6709\u4e0d\u826f\u540e\u679c<sup>\u30103\u3011<\/sup>\u3002\u6bd4\u5982\uff0cBanki \u7b49<sup>\u30104\u3011<\/sup>\u62a5\u9053\u5728\u98df\u7ba1\u764c\u624b\u672f\u5207\u9664\u7684\u75c5\u4eba\u4e2d\uff0c\u672f\u540e\u82e5 cfDNA 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\u7247\u6bb5\u7684\u957f\u5ea6\u5206\u5e03\u4e0e\u5065\u5eb7\u4eba\u4e0d\u540c<sup>\u30105\u3011<\/sup>\u3002\u57fa\u4e8e\u8fd9\u4e2a\u73b0\u8c61\uff0cDNA\u201c\u5b8c\u6574\u6027\u6307\u6570\u201d\u754c\u5b9a\u4e3a\u8f83\u957f DNA \u788e\u7247\u4e0e\u8f83\u77ed DNA \u788e\u7247\u7684\u6bd4\u7387\uff0c\u662f cfDNA \u6765\u6e90\u7684\u6307\u5f81\uff0c\u53ef\u5728\u6d53\u5ea6\u57fa\u7840\u4e0a\u8fdb\u4e00\u6b65\u4fee\u6b63\u80bf\u7624\u8d1f\u8377\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image aligncenter size-large is-resized\"><img decoding=\"async\" loading=\"lazy\" src=\"https:\/\/www.helixmatrix.net\/wp-content\/uploads\/2022\/11\/pianduan-2-990x1024.jpg\" alt=\"\" class=\"wp-image-185\" width=\"645\" height=\"666\" srcset=\"https:\/\/www.helixmatrix.net\/wp-content\/uploads\/2022\/11\/pianduan-2-990x1024.jpg 990w, https:\/\/www.helixmatrix.net\/wp-content\/uploads\/2022\/11\/pianduan-2-290x300.jpg 290w, https:\/\/www.helixmatrix.net\/wp-content\/uploads\/2022\/11\/pianduan-2-768x794.jpg 768w, https:\/\/www.helixmatrix.net\/wp-content\/uploads\/2022\/11\/pianduan-2.jpg 1016w\" sizes=\"(max-width: 645px) 100vw, 645px\" \/><\/figure>\n\n\n\n<p>\u87ba\u65cb\u77e9\u9635\u516c\u53f8\u901a\u8fc7\u7ed3\u5408cfDNA\u7247\u6bb5\u957f\u5ea6\u7684\u5206\u5e03\u60c5\u51b5\u7ed3\u5408\u4ee3\u8c22\u7ec4\u5b66\u6570\u636e\uff0c\u53ef\u4ee5\u5927\u5e45\u63d0\u9ad8\u7b5b\u67e5\u51c6\u786e\u6027\uff0c\u76ee\u524d\u6b63\u5728\u5c71\u4e1c\u7b2c\u4e00\u533b\u79d1\u5927\u5b66\u9644\u5c5e\u7701\u7acb\u533b\u9662\u8fdb\u884c\u5927\u89c4\u6a21\u4e34\u5e8a\u5b9e\u9a8c\u3002<\/p>\n\n\n\n<blockquote class=\"wp-block-quote\">\n<p>1. Lo YM, Zhang J, Leung TN, Lau TK, Allan MZ, Chang N et al (1999) Rapid clearance of fetal DNA from maternal plasma. Am J Hum Genet 64:218\u2013224.<\/p>\n\n\n\n<p>2. Steinman CR\uff0eFree DNA in serum and plasma from normal adults[J]\uff0eJ Clin Invest\uff0c1975\uff0c56(2)\uff1a512-515\uff0e<\/p>\n\n\n\n<p>3. van der Drift MA\uff0cHol HE\uff0cKlaassen CH\uff0cet al\uff0eCirculating DNA is a non-invasive prognostic factor for survival in non-small cell lung cancer\uff0eLung Cancer\uff0c2010\uff0c68(2)\uff1a283-287.<\/p>\n\n\n\n<p>4. Banki F\uff0cYacoub W N\uff0cHagen JA\uff0cet al\uff0ePlasma DNA is more reliable than carcinoembryonic antigen for diagnosis of recurrent esophageal cancer\uff0eJ Am Coll Surg\uff0c2008\uff0c207(1)\uff1a30-35.<\/p>\n\n\n\n<p>5. underhill et al.Fragment Length of Circulating Tumor DNA. PLOS Genetics,2016.<\/p>\n<\/blockquote>\n","protected":false},"excerpt":{"rendered":"<p>cfDNA\uff08cell free DNA\uff09\u6307\u5b58\u5728\u4e8e\u4eba\u4f53\u8840\u6db2\u5faa\u73af\u4e2d\u7684\u3001\u6e38\u79bb\u4e8e\u7ec6\u80de\u5916\u7684\u9ad8\u5ea6\u7247\u6bb5\u5316DNA\u3002\u5728\u7279\u5b9a\u60c5\u51b5\u4e0b [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":179,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[5],"tags":[],"_links":{"self":[{"href":"https:\/\/www.helixmatrix.net\/index.php\/wp-json\/wp\/v2\/posts\/177"}],"collection":[{"href":"https:\/\/www.helixmatrix.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.helixmatrix.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.helixmatrix.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.helixmatrix.net\/index.php\/wp-json\/wp\/v2\/comments?post=177"}],"version-history":[{"count":2,"href":"https:\/\/www.helixmatrix.net\/index.php\/wp-json\/wp\/v2\/posts\/177\/revisions"}],"predecessor-version":[{"id":702,"href":"https:\/\/www.helixmatrix.net\/index.php\/wp-json\/wp\/v2\/posts\/177\/revisions\/702"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.helixmatrix.net\/index.php\/wp-json\/wp\/v2\/media\/179"}],"wp:attachment":[{"href":"https:\/\/www.helixmatrix.net\/index.php\/wp-json\/wp\/v2\/media?parent=177"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.helixmatrix.net\/index.php\/wp-json\/wp\/v2\/categories?post=177"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.helixmatrix.net\/index.php\/wp-json\/wp\/v2\/tags?post=177"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}